Phospho stat4
WebKeyTec®TR-FRET Phospho-STAT4 (Y693) Kit : KeyTec®TR-FRET Phospho-STAT5 (Y694/Y699) Kit : KeyTec®TR-FRET Total STAT5 Kit : KeyTec®TR-FRET Phospho-STAT6 (Y641) Kit : KeyTec®TR-FRET Total STAT6 Kit : KeyTec®TR-FRET Phospho-4EBP1 (T37/T46) Kit : KeyTec®TR-FRET Total 4EBP1 Kit : KeyTec®TR-FRET Phospho-BTK … WebHuman Phospho-STAT4 (Y693) Antibody Summary Species Reactivity Human Specificity Detects human STAT4 when phosphorylated at Y693. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human Phospho-STAT4 Y693 site Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Phospho stat4
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WebSTAT4 is expressed in subset of tissues including spleen, heart, brain, peripheral blood cells and testis. STAT4 is involved in mediating IL-12 response in lymphocytes and regulating T helper cell differentiation. Long Name: Signal Transducer and Activator of Transcription 4 Entrez Gene IDs: 6775 (Human); 20849 (Mouse) Alternate Names: WebSTAT4 forms homodimers and heterodimers with related STAT family members. Tyrosine phosphorylated STAT4 can bind the IFN-gamma activated site (GAS). Serine phosphorylation of STAT is also required for maximal transcriptional activity. STAT4 expression is restricted to the thymus, spleen and testis.
WebJun 15, 2001 · The decrease of STAT4 protein appears to be due to specific degradation of phospho-STAT4, possibly through the proteasome degradation pathway. Decreased levels of STAT4 protein lead to decreased STAT4 DNA-binding activity and reduced proliferation and secretion of IFN-gamma. This down-regulation of STAT4 is specific for IL-12 … WebIL-12 selectively regulates STAT4 via phosphatidylinositol 3-kinase and Ras-independent signal transduction pathways IL-12 is an important immunomodulatory cytokine that …
WebFeb 19, 2024 · Little is known about the effects on hyaluronan (HA) metabolism of UVA radiation. This study demonstrates that the secretion of HA by human dermal fibroblasts (HDFs) is downregulated by UVA, accompanied by the down- and upregulation of mRNA and protein levels of the HA-synthesizing enzyme (HAS2) and the HA-degrading protein, … WebKeyTec®TR-FRET Phospho-STAT4 (Y693) Kit : KeyTec®TR-FRET Phospho-STAT5 (Y694/Y699) Kit : KeyTec®TR-FRET Total STAT5 Kit : KeyTec®TR-FRET Phospho-STAT6 …
WebDec 21, 2012 · We used immunohistochemistry with phospho-specific antibodies to look at the presence of activated JAK2 and STAT3 in human tissues, BTSCs, and tumors from …
WebSynthetic peptide within Human STAT4 (phospho Y693). The exact sequence is proprietary. A phospho specific peptide corresponding to residues surrounding Y693 of Human STAT4. Database link: Q14765 Positive control IL4-treated HepG2 cell extract; Human breast carcinoma tissue. General notes litehouse spring onionWebUnconventionally, during RNA virus infection, STAT4 was found unphosphorylated in the cytoplasm of macrophages. Mechanistically, STAT4 interacts with E3 ligase CHIP, which … litehouse solo tentWebFabgennix Anti-Phospho-STAT4 (Ser721) Polyclonal, Catalog # PSTAT4-440AP. Tested in Western Blot (WB), Immunoprecipitation (IP) and ELISA (ELISA) applications. This … impey care solutionsWebA key component in the activation of Stat4 is the phosphorylation on tyrosine and serine residues in response to IL-12 stimulation. IL-12 stimulation leads to the phosphorylation … impey aqua mat underfloor heatingWebPhospho-MAPK Family ELISA Sampler Pack Pim Kinase ELISA Sampler Pack Pyroptosis ELISA Sampler Pack Reactive Cell Death and Autophagy ELISA Sampler Pack Reactive Inflammasome ELISA Sampler Pack Receptor Tyrosine Kinase ELISA Sampler Pack SARS-CoV-2 Virus-Host Interaction ELISA Sampler Pack impey bathroom productshttp://www.biotnt.com/product/product_799435.html impey curtain railWebSTAT4, which requires phosphorylation at tyrosine 693 for activation, plays a pivotal role in the differentiation and proliferation of Th1 and Th17 cells, both of which are crucial … litehouse sweet onion dressing \\u0026 marinade