WebThe Tg(Tff1-CreERT2;Tff2-rtTA;Tff3-Luc) strain confers tamoxifen-inducible irreversible somatic recombination and allows simultaneous doxycycline-dependent reversible gene … Web25 Oct 2016 · The Tg(Tff1-CreERT2;Tff2-rtTA;Tff3-Luc) strain confers tamoxifen-inducible irreversible somatic recombination and allows simultaneous doxycycline-dependent reversible gene activation in the gastric epithelium of developing and adult mice. This strain also confers luciferase activity to the intestinal epithelium to enable in vivo …
Tff1-2A-CreERT2 - Model Org
Web16 Sep 2024 · Here, they play different roles for mucosal protection and the innate immune defense: TFF1 is a gastric tumor suppressor; TFF2 builds a lectin complex with the mucin … WebAccepted Article Thiem et al. Murine model for gastric-specific gene modifications Inducible gene modification in the gastric epithelium of Tff1-CreERT2;Tff2-rtTA;Tff3-Luc mice Stefan Thiem 1*, Moritz F. Eissmann , Emma Stuart 2, Joachim Elzer 1, Anna Jonas 3, Michael Buchert and Matthias Ernst 1, # 1 Cancer and Inflammation Laboratory, Olivia Newton … lat mutter
Tff1-2A-CreERT2
Web6 May 2024 · TFF1 is mainly expressed in gastric surface mucous cells (together with the mucin MUC5AC), TFF2 is—together with MUC6—restricted to gastric mucous neck cells, antral gland cells and duodenal Brunner’s glands, whereas TFF3 is a typical product of intestinal goblet cells and most other mucous epithelia and their glands. Web31 Aug 2024 · Lineage tracing studies using transgenic Tff1-CreERT2 and Tff1-Cre mice showed that Tff1 is also expressed in long-lived stem and progenitor cells of the gastric … Webthe Tg(Tff1-CreERT2;Tff2-rtTA;Tff3-Luc) strain can confer intermittent transgene expression to gastric epithelial cells that have undergone previous gene modification, and may be … lat 64 savior